Shopping Cart

Your cart is currently empty

Why Coenzymated B Vitamins Are Superior: Unlocking the Power of Enhanced Bioavailability and Digestibility

Designs For Health Designs for Health B-Supreme



Coenzymated B vitamins are a superior form of B vitamins that are directly usable by the body. Unlike other forms of B vitamins, which need to be converted before the body can utilize them, coenzymated B vitamins are already in their active forms, making them more bioavailable and digestible.Numerous studies support the effectiveness of coenzymated B vitamins in promoting cellular functioning, brain health, and neurological conditions.

B vitamins are essential for the body's overall health and well-being. They play a crucial role in energy production, brain function, and the synthesis of important molecules such as neurotransmitters and myelin. However, not all B vitamins are created equal. The form in which they are consumed can greatly impact their bioavailability and effectiveness in the body. This is where coenzymated B vitamins shine.


Coenzymated B Vitamins

Coenzymated B vitamins exist in their active state, such as methylcobalamin (B12) and pyridoxal-5-phosphate (B6). These active forms of B vitamins are crucial for cellular functioning, energy metabolism, antioxidative effects, and the synthesis of myelin and neurotransmitters.While some research has focused on a subset of B vitamins involved in homocysteine metabolism, it is important to note that other B vitamins are equally essential for overall health.

For example, coenzymated B12, also known as methylcobalamin, is the active form of vitamin B12 that is directly usable by the body. It plays a key role in the synthesis of DNA, red blood cell production, and the maintenance of nerve cells. Coenzymated B6, or pyridoxal-5-phosphate, is the active form of vitamin B6 and is involved in over 100 enzymatic reactions in the body, including the metabolism of amino acids and the production of neurotransmitters like serotonin and dopamine.


Bioavailability and Digestibility of Coenzymated B Vitamins

Coenzymated B vitamins have enhanced bioavailability, meaning that they are more readily absorbed and utilized by the body compared to other forms. This is why the B Supreme supplement is the most recommended by our healers at Thrive. This is particularly significant because deficiencies or insufficiencies in B vitamins are common in developed countries. The improved bioavailability of coenzymated B vitamins ensures that the body can efficiently utilize them for energy production, brain function, and DNA synthesis.

To put it into perspective, let's compare the bioavailability of coenzymated B vitamins with their non-coenzymated counterparts. For instance, non-coenzymated forms of B vitamins, such as cyanocobalamin (B12) and pyridoxine (B6), need to be converted by the body into their active forms before they can be used. This conversion process requires specific enzymes and can be inefficient for some individuals, leading to suboptimal absorption and utilization of these vitamins. Coenzymated B vitamins, on the other hand, bypass this conversion step, making them more bioavailable and easier for the body to digest and utilize.


Benefits of Coenzymated B Vitamins

Coenzymated B vitamins play a crucial role in maintaining neurological health, nerve conduction velocity, and myelin synthesis. They support healthy cognitive function, neurotransmitter synthesis, and overall brain health. Additionally, B vitamins act as coenzymes in cellular processes, promoting energy production and aiding in the metabolism of fats and cholesterol.

For example, coenzymated B vitamins have been shown to be beneficial for individuals with neurological conditions such as peripheral neuropathy. Peripheral neuropathy is a condition characterized by damage to the peripheral nerves, resulting in symptoms such as numbness, tingling, and pain in the affected areas. Studies have found that coenzymated B vitamins can help improve nerve conduction velocity and reduce symptoms in individuals with peripheral neuropathy.

Furthermore, coenzymated B vitamins have been found to support brain health and cognitive function. Research suggests that B vitamins, particularly coenzymated forms, play a crucial role in neurotransmitter synthesis, which is essential for optimal brain function. They have also been associated with a reduced risk of age-related cognitive decline and neurodegenerative diseases such as Alzheimer's disease.


Studies and Research Supporting the Superiority of Coenzymated B Vitamins

Research has shown that B vitamins, including coenzymated forms, have synergistic effects in the nervous system and can improve certain neurological conditions. Deficiencies in B vitamins have been associated with peripheral neuropathy and neurological disorders. Insufficiencies in folate, vitamin B12, and vitamin B6 have been implicated in elevated homocysteine levels, which can contribute to cardiovascular and cognitive diseases. Clinical trials investigating the effects of B vitamin supplementation on homocysteine levels and disease outcomes have yielded mixed results.

For example, a study published in the Journal of Neurology, Neurosurgery & Psychiatry found that supplementation with coenzymated B vitamins, specifically B12 and folic acid, helped improve cognitive function in older adults with mild cognitive impairment. Another study published in the Journal of the American Medical Association (JAMA) found that high-dose B vitamin supplementation, including coenzymated forms, reduced the rate of brain atrophy in individuals with mild cognitive impairment.

While the results of some studies have been promising, it is important to note that more research is needed to fully understand the benefits of coenzymated B vitamins and their role in preventing and treating neurological conditions. Additionally, individual responses to B vitamin supplementation can vary, and it is important to consult with a healthcare professional before starting any new supplement regimen.



The enhanced bioavailability and digestibility of coenzymated B vitamins make them a superior choice for individuals seeking optimal cellular functioning, brain health, and neurological support. Incorporating coenzymated B vitamins into your supplement regimen can provide the benefits of their superior effectiveness.

While further research is needed to fully understand the extent of their benefits, the existing studies suggest that coenzymated B vitamins have the potential to support neurological health, enhance cognitive function, and improve overall well-being. Whether you're looking to support brain health, maintain energy levels, or address specific neurological conditions, coenzymated B vitamins are a promising option to consider. Remember to consult with a healthcare professional to determine the appropriate dosage and ensure it aligns with your individual needs and health goals.


Learn more about B vitamins in our other blog posts:

How B vitamins boost energy

The role of B vitamins in athletic performance

B Vitamins and Oxidative Stress


Check out our favorite coenzymated B vitamin in our shop!